"As it turns out, not only can we reverse the aging process at the cellular level now, and actually do it quite simply and quickly, but we can also reverse aging at the system level and the organ level. And for that matter, we can reverse it in terms of how we look and feel, and by that I mean our skin and hair and energy levels. This also affects our life span as well. There are a number of nutraceuticals that can play a role, but three stand out: L-carnosine, dimethylaminoethanol (DMAE), and acetyl-L-carnitine. Based on everything we know, supplementing with a combination of these nutrients is one of the most effective and safest steps we can take to help turn back the clock at the cellular level.
L-Carnosine
L-Carnosine is a naturally occurring combination of two amino acids, alanine and histadine, that was discovered in Russia in the early 1900s. Because much of the research was done in Russia, it was largely unavailable in the United States until just a few years ago. Now, though, there have been a number of studies and experiments in other parts of the world verifying everything done in Russia, and more. Most notably, there were a series of astonishing experiments done in Australia that proved that carnosine rejuvenates cells as they approach senescence. Cells cultured with carnosine lived longer and retained their youthful appearance and growth patterns.
L-Carnosine is a naturally occurring combination of two amino acids, alanine and histadine, that was discovered in Russia in the early 1900s. Because much of the research was done in Russia, it was largely unavailable in the United States until just a few years ago. Now, though, there have been a number of studies and experiments in other parts of the world verifying everything done in Russia, and more. Most notably, there were a series of astonishing experiments done in Australia that proved that carnosine rejuvenates cells as they approach senescence. Cells cultured with carnosine lived longer and retained their youthful appearance and growth patterns.
It was discovered that carnosine can actually reverse the signs of aging in senescent cells. When the scientists transferred senescent cells to a culture medium containing carnosine, those cells exhibited a rejuvenated appearance and often an enhanced capacity to divide. When they transferred the cells back to a medium lacking carnosine, the signs of senescence quickly reappeared. In other words, the carnosine medium restored the juvenile cell phenotype within days, whereas the standard culture medium brought back the senescent cell phenotype. In addition, the carnosine medium increased cell life span, even for old cells. When the researchers took old cells that had already gone through 55 divisions and transferred them to the carnosine medium, they survived up to 70 divisions, compared to only 57-61 divisions for the cells that were not transferred. This represents an increase in the number of cell divisions for each cell of almost 25 percent. But in terms of cell life, the increase was an astounding 300 percent. The cells transferred to the carnosine medium attained a life span of 413 days, compared to just 126-139 days for the control cells."
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