"According to the cholesterol theory of heart disease (and despite all that you may have heard, it is only a theory), LDL cholesterol in the blood combines with other substances such as cellular waste products, calcium, and fibrin (a clotting protein) to form arterial plaque, which attaches itself to the inner lining of the arteries. Over time, cholesterol plaque causes thickening of the artery walls and narrowing of the arteries, a process called atherosclerosis. Arteries that supply blood and oxygen to the heart muscles are called coronary arteries. When coronary arteries are narrowed by atherosclerosis, they are incapable of supplying enough blood and oxygen to the heart muscle during exertion. Lack of oxygen to the heart muscle (ischemia) causes chest pain. Formation of a blood clot in a coronary artery can clause complete blockage of that artery, leading to death of heart muscle tissue--a heart attack. (Of course, an artery significantly narrowed by atherosclerosis is that much more easily blocked by a blood clot.) Atherosclerotic disease of the coronary arteries (coronary heart disease) is the most common cause of death in the United States, accounting for about 750,000 deaths annually."
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thanks for feedback, hope from U to share this!