"Acetyl-L-Carnitine
Like DMAE, acetyl-L-carnitine (ALC) is a perfect complement to L-carnosine. Although your body can synthesize L-carnitine in the liver, it depends on outside sources (meat being a primary one) to fulfill its requirements. This can present a problem for vegetarians since L-carnitine performs several key functions in the human body. For one, it can improve the functioning of the immune system by enhancing the ability of macrophages to function as phagocytes. And it can improve the functioning of muscle tissue and has been shown to increase running speed when given prior to exercise. It also plays a major role in cellular energy production by shuttling fatty acids from the main cell body into the mitochondria (the cell’s energy factories) so that the fats can be oxidized for energy. Without carnitine, fatty acids cannot easily enter the mitochondria.
Like DMAE, acetyl-L-carnitine (ALC) is a perfect complement to L-carnosine. Although your body can synthesize L-carnitine in the liver, it depends on outside sources (meat being a primary one) to fulfill its requirements. This can present a problem for vegetarians since L-carnitine performs several key functions in the human body. For one, it can improve the functioning of the immune system by enhancing the ability of macrophages to function as phagocytes. And it can improve the functioning of muscle tissue and has been shown to increase running speed when given prior to exercise. It also plays a major role in cellular energy production by shuttling fatty acids from the main cell body into the mitochondria (the cell’s energy factories) so that the fats can be oxidized for energy. Without carnitine, fatty acids cannot easily enter the mitochondria.
Acetyl-L-carnitine is a specialized form of L-carnitine that is often deficient, even in meat eaters. It performs virtually all of the same functions as L-carnitine, only better. In terms of cellular energy production, in addition to shuttling fatty acids into cell mitochondria, ALC provides acetyl groups from which acetyl-coenzyme A (a key metabolic intermediate) can be regenerated. This is important because acetyl-coenzyme A facilitates the transport of metabolic energy and boosts mitochondrial activity. Also, the addition of the acetyl group makes ALC water soluble, which enables it to diffuse across the inner wall of the mitochondria and to cross all cell membranes more easily. In particular, ALC readily crosses the blood-brain barrier, where it provides a number of specialized neurological functions. Studies have shown that acetyl-L-carnitine can inhibit the deterioration in mental function associated with Alzheimer’s disease and slow its progression. Part of this is a result of its ability to shield neurons from the toxicity of beta amyloid protein. As a result, ALC improves alertness in Alzheimer’s patients."
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